HSDD Drug Flibanserin (Addyi) Side Effects and Dosage


Hypoactive sexual desire disorder can be present in both men and women, but, this article will only address the issue in women. HSDD in women can be treated with therapy and medication, or a combination of both. However, this article will only explore the effectiveness of flibanserin (Addyi) as an HSDD medication.

What is HSDD?
HSDD Drug Flibanserin (Addyi) Side Effects and Dosage
Now commonly referred to as female sexual arousal disorder, hypoactive sexual desire disorder is abbreviated as HSDD. As the name implies, it is a sexual dysfunction characterized by low sexual desire or inability to experience sexual arousal easily. Both men and women can suffer from HSDD, however, it is twice as common in women as in men. It is the most common sexual disorder that women suffer, especially in women who have reached menopause.

Often women experience fluctuations in sexual desire or libido over the years of their lives. This kind of drop in libido that occurs as a result of psychological factors like stress or physical changes like pregnancy and health issues, gets fixed after some time. For HSDD to be diagnosed, the symptoms must be severe enough to disrupt a person’s normal life for a significant period of time.

HSDD symptoms
Although the main complaint is an inability to feel arousal or a lack of libido, HSDD is diagnosed based on the following symptoms.

  • decreased or complete lack of sexual desire
  • Decreased or complete reduction of sexual fantasies towards sexual partners or other persons
  • lack of interest in initiating sexual activity
  • Reduced or full capacity in the ability to perceive stimuli
  • Reduced or full capacity to experience pleasure from sexual stimulation

These symptoms must be severe enough to cause personal distress or distress in the relationship with the romantic partner. Symptoms must have been present for six consecutive months for the diagnosis to be considered.

What causes HSDD?
HSDD Drug Flibanserin (Addyi) Side Effects and Dosage
Since women’s sexual desire depends on many more factors than men’s sexual desire, it can be influenced by many factors and it is sometimes difficult to pinpoint a single cause of low libido or the inability to experience arousal. could. Is. Generally the following reasons can cause HSDD:

  • Physiological factors such as hormonal imbalance, changes in neurochemicals, gynecological diseases and gynecological conditions such as pregnancy, upcoming menopause.
  • Psychological factors such as work-related stress, complications in a romantic relationship, or distress in other aspects of life.
  • Drug-induced HSDD can be caused by birth control pills, antidepressants, SSRIs, SNRIs, and many other drugs.

Treatment of HSDD should be led by the determined cause of HSDD, if therapy can resolve the decline in sexual desire, it should definitely be considered as the first line of action and HSDD added depending on the need for medication should go.

How is HSDD treated?
While there are many pills like Viagra and many other treatment options for sexual problems faced by men, there are very few treatment options for women. Unfortunately for a very long time no attention was paid to female sexual disorders or even to female sexual experiences. The medical science and research communities work in the direction from which they receive funding. While there was little debate or market for the treatment of HSDD, apparently no advances had been made in medicine. So only in the past decade, has the feminist movement struggled to highlight this lack of medical scientists in addressing the sexual issues facing men.

That’s why the Food and Drug Administration was hesitant to approve flibanserin as a prescription drug for HSDD in 2016, when the FDA twice rejected it, calling the drug an “even day”. Asked to approve by. Score” campaign was launched. Women just wanted something that would give them some hope of relief from symptoms considered “normal” for premenopausal women.

There is currently a lack of scientific research available to testify to their effectiveness and to measure their value when weighed against potential side effects. These include the well-known pink pill Addyi, bremelanotide, or Vyleesi (self-administered injections) and O Shots (derived from platelet rich plasma therapy PRP).

What is flibanserin (Addyi)?
Flibanserin Review
Often referred to as the pink pill, Flibanserin is a drug approved by the Food and Drug Administration (FDA) to treat women with HSDD. Flibanserin is a postsynaptic serotonin-1A (5HT-1A) receptor agonist and 5HT-2A receptor antagonist and was originally tested as an anti-depressant. It is commonly marketed as Addyi.

pink pill vs blue pill
HSDD Natural Remedies
It is important to understand that Addyi is not female Viagra, because Viagra for men cures erectile dysfunction, the problem; “The inability to achieve or maintain an erection strong enough to have intercourse”. male hunting

With this problem, there is still sexual desire and can experience pleasure, they can get aroused as much as possible but cannot keep their penis up and erect. On the other hand, HSDD is the inability to experience sexual desire or arousal.

Addyi Vs Aphrodisiac
It is also important to understand that flibanserin is not a drug to increase libido and is therefore not considered an aphrodisiac. This is a prescription for treating the symptoms of HSDD. Even, in theory, this would unblock pre-existing neurotransmitter receptors that affect libido but it would not stimulate increased production of neurotransmitters or result in achieving libido levels that never was not.

Does flibanserin (ADD) work?
Some studies have shown that this drug shows significant improvements in the frequency and intensity of pleasurable sexual experiences compared to placebo groups. Theoretically, it works to bring neurochemicals in the brain to “normal” levels. It aims to unblock the receptors that work to promote norepinephrine and dopamine activity, and also regulate the production of serotonin. These neurotransmitters are important in overall mood stability, however, there is a serious lack of scientific research supporting Addyi as an effective treatment for HSDD.

Available research is clearly funded by pharmaceutical companies and thus their credibility is questionable.

What is the recommended dosage for Addyi?
It is recommended that the doctor prescribes one tablet per day to be taken either in the evening or at night. Addyi is to be taken regularly every day, even if you do not plan or intend to be physically intimate that day. Even if you are not sexually active every day of the week, you will still need to take the pink pill every day. This is why medication has lower compliance rates as many women find it difficult to commit to medication and prefer need-based shots aka Vialacea.

What are the side effects of flibanserin (Addyi)?
The common side effects of Addyi are similar to those of other neuropharmacological drugs, including dizziness, flushing, nausea, dry mouth, and fatigue. Risk of drug interactions with alcohol, hormonal birth control methods, and yeast infection medication. There have been cases of women taking Addyi and passing out after drinking alcohol. It is important that the doctor and patient sit down and discuss the benefits and risks and after weighing all the aspects, take a decision to prescribe Flibanserin as an HSDD medication.

Given that Addyi was effective in the treatment of drug-induced HSDD, it was tested for safety with respect to drug interactions with SSRIs and SNRIs, and found to be safe.

Who should not take Addyi?
If you do not experience an improvement in your symptoms after two months of taking the medicine, you should stop taking the medicine. Addyi should not be prescribed to individuals suffering from liver and heart disease, autoimmune diseases and blood pressure problems. It should also not be prescribed to women under treatment for vaginal infection or any fungal infection. Flibanserin is not recommended for pregnant women or breastfeeding mothers and has only been tested for premenopausal women. Its effectiveness or side effects for post-menopausal women are yet unknown.

Other HSDD medication and treatment options available
Bremelanotide (Vyleesi) is a self-administered shot that you give yourself 45 minutes before you plan to engage in sexual activity. These injections are approved by the FDA but it is recommended that you use no more than eight shots in a month. O shots are injections of platelet-rich plasma that are administered by a certified doctor around and inside the walls of your vagina. It is claimed that they improve HSDD symptoms such as vaginal dryness within a week of administration. Treatment promises better, stronger, more frequent orgasms, increased sexual desire and effects can last for a year or more.

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